Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMQTLVB)

Drug Name
Hebergel Drug Info
Synonyms Interferon alpha 2b gel (viral infection), CIGB
Indication
Disease Entry ICD 11 Status REF
Virus infection 1A24-1D9Z Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMQTLVB

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interferon-alpha 2 (IFNA2) TTSIUJ9 IFNA2_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Interferon-alpha 2 (IFNA2) DTT IFNA2 2.609 1.678 0.263 0.379
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Virus infection
ICD Disease Classification 1A24-1D9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Interferon-alpha 2 (IFNA2) DTT IFNA2 9.31E-04 0.35 2.05
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Detection of PEGylated proteins in polyacrylamide gels by reverse staining with zinc and imidazole salts. Electrophoresis. 2008 Jun;29(11):2363-71.
2 Evaluation of recombinant human interferon alpha-2b structure and stability by in-gel tryptic digestion, H/D exchange and mass spectrometry. J Pharm Biomed Anal. 2006 Feb 24;40(3):781-7.