Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMQX5UA)

Drug Name
FLX-787 Drug Info
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Phase 2 [1]
Multiple sclerosis 8A40 Phase 2 [2]
Muscle spasm MB47.3 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMQX5UA

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Melanoma antigen gp75 (TYRP1) TTFRV98 TYRP1_HUMAN Activator [2]
Transient receptor potential channel (TRP channel) TT79AOF NOUNIPROTAC Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Melanoma antigen gp75 (TYRP1) DTT TYRP1 4.94 5.479 6.092 6.695
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Amyotrophic lateral sclerosis
ICD Disease Classification 8B60.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Melanoma antigen gp75 (TYRP1) DTT TYRP1 7.82E-01 0.53 0.21
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)