Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMR8Y4F)

Drug Name
Troplasminogen alfa Drug Info
Synonyms TAPgen; BB-10153; Thrombin activatable plasminogen, British Biotech; Thrombin activatable plasminogen, Vernalis
Indication
Disease Entry ICD 11 Status REF
Myocardial infarction BA41-BA43 Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMR8Y4F

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Plasminogen (PLG) TTP86E2 PLMN_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Plasminogen (PLG) DTT PLG 11.754 0.848 8.393 2.138
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Myocardial infarction
ICD Disease Classification BA41-BA43
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Plasminogen (PLG) DTT PLG 8.61E-01 -0.01 -0.09
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00144014) Safety and Efficacy Study in Acute Ischaemic Stroke. U.S. National Institutes of Health.
2 V-10153 (Vernalis). Curr Opin Investig Drugs. 2005 Sep;6(9):951-5.