Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRE96F)

Drug Name

Benzomate Drug Info

Synonyms

Benzoxamate; Acarmate; Artaban; Citrazon; Azomate; Benzoximate [BSI:ISO]; UNII-32TAI9ZK5N; 32TAI9ZK5N; NA-53M; NA-53; EINECS 249-439-1; BRN 2783319; BENZOHYDROXAMIC ACID, O-BENZOYL-3-CHLORO-2,6-DIMETHOXY-N-ETHYL-; Benzoic acid, anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzimidic acid; AC1L1RMU; 67011-39-6; SCHEMBL9806359; HOERQTQCTISLFR-UHFFFAOYSA-N; LS-35432; C19021; N-(Benzoyloxy)-3-chloro-N-ethyl-2,6-dimethoxybenzamide; Benzoic acid anhydride with 3-chloro-N-ethoxy-2,6-dimethoxybenzenecarboximidic acid (9CI); Benzoic aci

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6035168
CAS Number: CAS 29104-30-1
TTD Drug ID: DMRE96F

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steryl-sulfatase (STS)	TTHM0R1	STS_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steryl-sulfatase (STS)	DTT	STS	4.722	6.048	5.125	4.768

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steryl-sulfatase (STS)	DTT	STS	1.80E-38	-0.79	-1.15

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase. Bioorg Med Chem. 2004 May 15;12(10):2759-72.