Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRGM21)

Drug Name
4-(4-isopropylphenyl)-5-cyano-2H-1,2,3-triazole Drug Info
Synonyms CHEMBL239895; 4-(4-isopropylphenyl)-5-cyano-2H-1,2,3-triazole; SCHEMBL17969081
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44437844
TTD Drug ID
DMRGM21

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ERBB2 messenger RNA (HER2 mRNA) TTR5TV4 ERBB2_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ERBB2 messenger RNA (HER2 mRNA) DTT ERBB2 3.50E-77 0.49 1.12
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Synthesis and biological evaluation of 4-aryl-5-cyano-2H-1,2,3-triazoles as inhibitor of HER2 tyrosine kinase. Bioorg Med Chem. 2007 Feb 1;15(3):1533-8.