Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRHQTU)

Drug Name
PSMA subunit vaccine Drug Info
Synonyms
Recombinant soluble PSMA vaccine; RsPSMA vaccine; PSMA subunit vaccine (prostate cancer); PSMA recombinant soluble protein vaccine, CYTOGEN/Progenics; PSMA rs protein vaccine, CYTOGEN/Progenics; PSMA protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA purified protein vaccine (prostate cancer), Progenics/CYTOGEN; PSMA subunit vaccine (prostate cancer), Progenics/CYTOGEN; PSMA-based therapeutics, CYTOGEN/Progenics
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMRHQTU

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutamate carboxypeptidase II (GCPII) TT9G4N0 FOLH1_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Glutamate carboxypeptidase II (GCPII) DTT FOLH1 6.894 4.758 5.651 9.837
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Prostate
The Studied Disease Prostate cancer [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glutamate carboxypeptidase II (GCPII) DTT FOLH1 1.40E-09 2.08 2.21
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Clinical pipeline report, company report or official report of Alphavax.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606).