Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRVA94)

Drug Name
2-benzyl-N1-hydroxy-N3-(4-phenylbutyl)malonamide Drug Info
Synonyms CHEMBL220996; 2-benzyl-N1-hydroxy-N3-(4-phenylbutyl)malonamide; BDBM50197497
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
16115012
TTD Drug ID
DMRVA94

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aminopeptidase N (ANPEP) TTPHMWB AMPN_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Aminopeptidase N (ANPEP) DTT ANPEP 8.744 7.809 8.914 11.49
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aminopeptidase N (ANPEP) DTT ANPEP 8.84E-07 -0.3 -0.71
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents. J Med Chem. 2007 Mar 22;50(6):1322-34.