Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMRYX1P)

Drug Name

CEL-1000 Drug Info

Synonyms

CEL-1000C; DerG, CEL-SCI; Immunostimulant peptide, CEL-SCI; Peptide vaccine (Vaxcine, oral, herpes simplex virus infection); Peptide vaccine (Vaxcine, oral, herpes simplex virus infection), Infexion

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMRYX1P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
T-cell surface glycoprotein CD4 (CD4)	TTN2JFW	CD4_HUMAN	Not Available	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
T-cell surface glycoprotein CD4 (CD4)	DTT	CD4	6.916	5.411	5.066	5.635

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Solid tumour/cancer

ICD Disease Classification

2A00-2F9Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
T-cell surface glycoprotein CD4 (CD4)	DTT	CD4	9.36E-04	0.67	2.62

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	A small peptide (CEL-1000) derived from the beta-chain of the human major histocompatibility complex class II molecule induces complete protection against malaria in an antigen-independent manner. Antimicrob Agents Chemother. 2004 Jul;48(7):2455-63.