Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSA8RU)

Drug Name
Abatacept Drug Info
Synonyms Orencia (TN)
Indication
Disease Entry ICD 11 Status REF
Alopecia areata ED70.2 Approved [1]
Crohn disease DD70 Approved [2]
Multiple sclerosis 8A40 Approved [3]
Rheumatoid arthritis FA20 Approved [4]
Systemic lupus erythematosus 4A40.0 Approved [5]
Therapeutic Class
Antirheumatic Agents
Cross-matching ID
TTD Drug ID
DMSA8RU

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
T-lymphocyte activation antigen CD86 (FUN1) DTT CD86 3.818 5.594 4.466 5.426
Activation B7-1 antigen (CD80) DTT CD80 6.576 6.711 6.951 6.944
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

References

1 Alopecia Areata: a Comprehensive Review of Pathogenesis and Management. Clin Rev Allergy Immunol. 2018 Feb;54(1):68-87.
2 Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet. 2007 May 12;369(9573):1641-57.
3 Advances in immune checkpoint-based immunotherapies for multiple sclerosis: rationale and practice. Cell Commun Signal. 2023 Nov 9;21(1):321.
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6891).
5 Systemic Lupus Erythematosus Management in Pregnancy. Int J Womens Health. 2022 Feb 15;14:199-211.
6 Selective modulation of T-cell co-stimulation: a novel mode of action for the treatment of rheumatoid arthritis. Clin Exp Rheumatol. 2009 May-Jun;27(3):510-8.