Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMSGNM1)

Drug Name

Sideroxylonal C Drug Info

Synonyms

sideroxylonal C; CHEMBL453538; BDBM50241601

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Endothelial plasminogen activator inhibitor (SERPINE1)	TTTO43N	PAI1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Endothelial plasminogen activator inhibitor (SERPINE1)	DTT	SERPINE1	9.01	4.744	5.113	3.138

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Endothelial plasminogen activator inhibitor (SERPINE1)	DTT	SERPINE1	1.56E-01	0.05	0.14

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens. J Nat Prod. 1999 Feb;62(2):324-6.