Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMT57WC)

Drug Name
Tetrahydrozoline Drug Info
Synonyms Tyzine
Indication
Disease Entry ICD 11 Status REF
Ocular disease 1F00.1Z Approved [1]
Cross-matching ID
PubChem CID
5419
ChEBI ID
CHEBI:28674
CAS Number
CAS 84-22-0
TTD Drug ID
DMT57WC

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor alpha-2C (ADRA2C) TT2NUT5 ADA2C_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Adrenergic receptor alpha-2C (ADRA2C) DTT ADRA2C 5.013 2.379 5.594 2.07
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Ocular disease
ICD Disease Classification 1F00.1Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Adrenergic receptor alpha-2C (ADRA2C) DTT ADRA2C 1.76E-01 -0.06 -0.28
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline. Clin Toxicol (Phila). 2008 Feb;46(2):171-2.