Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTB41W)

Drug Name

(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE Drug Info

Synonyms

(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE; BIE; AC1OCAA0; SCHEMBL5898857; ICLKAUQIPVFHOI-UHFFFAOYSA-N; 3,4-dihydroxy-2-nitrobenzophenone; 4-benzoyl-3-nitrobenzene-1,2-diol; BIA-8-176; ZINC13677656; DB07462; (3,4-dihydroxy-2-nitrophenyl)phenylmethanone

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 6914595
TTD Drug ID: DMTB41W

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Catechol-O-methyl-transferase (COMT)	TTKWFB8	COMT_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Catechol-O-methyl-transferase (COMT)	DTT	COMT	8.791	7.048	7.478	7.165

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Catechol-O-methyl-transferase (COMT)	DTT	COMT	9.24E-02	0.17	1.09

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.