Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTCA2Z)

Drug Name

N-(4-methylthiazol-2-yl)benzamide Drug Info

Synonyms

N-(4-methylthiazol-2-yl)benzamide; N-(4-methyl-1,3-thiazol-2-yl)benzamide; 37529-67-2; N-(4-Methyl-thiazol-2-yl)-benzamide; CHEMBL209410; AC1LEZPY; BAS 00470405; Enamine_001521; TimTec1_007096; MLS001212480; SCHEMBL1270190; MolPort-000-432-004; HMS2828E18; HMS1554C12; HMS1398F03; ZINC5712475; BDBM50186335; AKOS000591433; AKOS002234121; MCULE-9983922498; DA-42608; SMR000514239; KB-109083; N-(4-Methylthiazol-2-yl)benzenecarboxamide; N-(4-methyl(1,3-thiazol-2-yl))benzamide; ST50002848; FT-0770347; EU-0040062; BB 0221669; SR-01000449566

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 695178
TTD Drug ID: DMTCA2Z

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
LOX-5 messenger RNA (ALOX5 mRNA)	TTSJ6Q4	LOX5_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
LOX-5 messenger RNA (ALOX5 mRNA)	DTT	ALOX5	4.966	5.133	5.358	6.128

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
LOX-5 messenger RNA (ALOX5 mRNA)	DTT	ALOX5	9.43E-03	0.14	0.28

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening. J Med Chem. 2007 May 31;50(11):2640-6.