Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTKU46)

Drug Name

Bismuth Drug Info

Synonyms

Bismut; Bismuto; Wismut; Bismuth standard for AAS; Bismuth standard for ICP; LTBB002773; Bismuth(III) nitrate solution; Bismuth, elemental; Bismuth-209; BISMUTH, 99.95%; BISMUTH, 99.999%; 83Bi

Indication

Disease Entry	ICD 11	Status	REF
Diarrhea	ME05.1	Approved	[1]

Therapeutic Class

Antidiarrheals

Cross-matching ID

PubChem CID: 5359367
ChEBI ID: CHEBI:33301
CAS Number: CAS 7440-69-9
TTD Drug ID: DMTKU46

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Serum albumin (ALB)	TTFNGC9	ALBU_HUMAN	Binder	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Serum albumin (ALB)	DTT	ALB	7.535	2.536	4.755	4.7

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Diarrhea

ICD Disease Classification

ME05.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Serum albumin (ALB)	DTT	ALB	7.92E-01	-0.07	-0.44

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The effect of histamine H2-receptor blockade on bismuth absorption from three ulcer-healing compounds. Gastroenterology. 1991 Oct;101(4):889-94.
2	Competitive binding of bismuth to transferrin and albumin in aqueous solution and in blood plasma. J Biol Chem. 2001 Mar 23;276(12):8829-35.