Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMTX0ZJ)

Drug Name
PMID19743866C51 Drug Info
Synonyms Ac-RLTbaLAR-H; GTPL8653; BDBM50314023
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
46883596
TTD Drug ID
DMTX0ZJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement factor B (CFB) TTA0P7K CFAB_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement factor B (CFB) DTT CFB 10.419 4.895 7.235 6.78
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement factor B (CFB) DTT CFB 1.63E-02 0.07 0.13
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Structure-activity relationships for substrate-based inhibitors of human complement factor B. J Med Chem. 2009 Oct 8;52(19):6042-52.