Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMU8OCN)

Drug Name
CS1-CAR T Therapy Drug Info
Indication
Disease Entry ICD 11 Status REF
Plasma cell myeloma 2A83.1 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMU8OCN

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SLAM family member 7 SLAMF7 (CS1) TT7ILZ1 SLAF7_HUMAN CAR-T-Cell-Therapy [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
SLAM family member 7 SLAMF7 (CS1) DTT SLAMF7 3.17 4.178 3.17 3.678
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Plasma cell myeloma
ICD Disease Classification 2A83.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
SLAM family member 7 SLAMF7 (CS1) DTT SLAMF7 9.74E-01 0.13 0.31
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT03710421) CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory Multiple Myeloma