Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMU9WG0)

• Drug Name: 6-bromo-1H-indazole Drug Info
• Synonyms: 6-bromo-1H-indazole; 79762-54-2; 6-Bromoindazole; 6-Bromo-2H-indazole; 1H-Indazole, 6-bromo-; CHEMBL247365; 1H-INDAZOLE,6-BROMO-; 1788080-23-8; 6-Bromo-1H-indazole, 97%; 6- Bromoindazole; PubChem7831; zlchem 1237; 6-broMo-1H indazole; 6-bromo-1-H-indazole; 6-bromanyl-1H-indazole; ACMC-209pi5; SCHEMBL5902; KSC376S4P; 6-Bromo-1H-indazole, 95%; AMBZ0200; AC1Q251Y; CTK2H6947; ZLE0012; DTXSID80591229; MolPort-029-084-056; WMKDUJVLNZANRN-UHFFFAOYSA-N; MolPort-000-001-819; ZINC8764137; KS-000002SJ; CS-D0757; BCP00386; ACN-S003161; ACT06505

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 17842471
  CAS Number: CAS 79762-54-2
  TTD Drug ID: DMU9WG0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase brain (NOS1)	TTZUFI5	NOS1_HUMAN	Inhibitor	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	6.085	5.844	5.849	5.806

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Discovery agent
• ICD Disease Classification: N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase brain (NOS1)	DTT	NOS1	5.20E-01	0.02	0.07

References

• [1] 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80.