Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUACZF)

Drug Name

(1-Amino-ethyl)-phosphinic acid Drug Info

Synonyms

1-Aminoethylphosphinic acid; AMINOETHYLPHOSPHINIC ACID; 74333-44-1; 71937-28-5; 1-Aminoethylphosphinate; (1-Aminoethyl)phosphonous acid; Aminoethylphosphinic acid [INCI]; Phosphinic acid, (1-aminoethyl)-; Phosphinic acid, P-(1-aminoethyl)-; AC1O4DZP; Phosphinic acid, (1-aminoethyl)-, (+/-)-; 1-aminoethyl phosphinic acid; SCHEMBL579981; (1-aminoethyl)phosphinic acid; (1-Aminoethyl)-phosphinic acid; CTK5D5277; TVKUNRSARHGLNB-UHFFFAOYSA-N; 1-aminoethyl-hydroxy-oxophosphanium; AKOS006273172; Phosphinic acid, (1-aminoethyl)-, (-)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 53957231
TTD Drug ID: DMUACZF

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aminopeptidase N (ANPEP)	TTPHMWB	AMPN_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.744	7.809	8.914	11.49

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.84E-07	-0.3	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6.