General Information of Drug (ID: DMUANK9)

Drug Name
GR-328713 Drug Info
Synonyms GW-320449X; GW-328713X
Indication
Disease Entry ICD 11 Status REF
Arteriosclerosis BD40 Discontinued in Phase 1 [1]
Cross-matching ID
PubChem CID
9888983
TTD Drug ID
DMUANK9

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Microsomal triglyceride transfer protein (MTTP) TTUS1RD MTP_HUMAN Modulator [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Microsomal triglyceride transfer protein (MTTP) DTT MTTP 8.358 4.828 4.644 9.121
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Arteriosclerosis
ICD Disease Classification BD40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Microsomal triglyceride transfer protein (MTTP) DTT MTTP 9.76E-02 0.13 0.68
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008868)
2 Patent CN101237870 B.