Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUDY7H)

Drug Name

PDC-31 Drug Info

Synonyms

PDC-31 (nasal, dysmenorrhea); PDC-31 (nasal, dysmenorrhea), PDC; THG-113 (nasal formulation, primary dysmenorrhea), PDC Biotech; THG-113.31 (nasal, primary dysmenorrhea), PDC Biotech

Indication

Disease Entry	ICD 11	Status	REF
Dysmenorrhea	GA34.3	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMUDY7H

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin F2-alpha receptor (PTGFR)	TTT2ZAR	PF2R_HUMAN	Antagonist	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin F2-alpha receptor (PTGFR)	DTT	PTGFR	0.379	2.744	3.609	1.138

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Dysmenorrhea

ICD Disease Classification

GA34.3

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin F2-alpha receptor (PTGFR)	DTT	PTGFR	8.25E-02	-0.05	-0.14

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 344).