Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUE4K3)

Drug Name

4,5,6,7-tetrabromo-1H-benzimidazole Drug Info

Synonyms

4,5,6,7-tetrabromobenzimidazole; TBBz; 577779-57-8; 4,5,6,7-Tetrabromo-Benzimidazole; 4,5,6,7-tetrabromo-1H-benzo[d]imidazole; CHEMBL373937; 2oxy; AC1NP4E4; SCHEMBL406945; CTK5I6050; DTXSID80408803; MolPort-003-850-464; LOEIRDBRYBHAJB-UHFFFAOYSA-N; HMS3260K22; ZINC2528524; Tox21_500140; BDBM50156669; TBBz, > MFCD04116202; 4,5,6,7-Tetrabromo-1Hbenzimidazole; LP00140; CCG-221444; NCGC00260825-01; NCGC00165910-02; NCGC00165910-01; RT-009016; FT-0674936

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5149739
CAS Number: CAS 577779-57-8
TTD Drug ID: DMUE4K3

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Casein kinase II alpha (CSNK2A1)	TTER6YH	CSK21_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Casein kinase II alpha (CSNK2A1)	DTT	CSNK2A1	5.162	6.628	6.981	6.144

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Casein kinase II alpha (CSNK2A1)	DTT	CSNK2A1	6.82E-04	0.29	2.43

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2. Bioorg Med Chem. 2009 Feb 15;17(4):1573-8.