Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUGFS3)

Drug Name

4r-Fluoro-N6-Ethanimidoyl-L-Lysine Drug Info

Synonyms

4R-FLUORO-N6-ETHANIMIDOYL-L-LYSINE; I58; AC1L9LS8; SCHEMBL4308483; DB01835; (4R)-N~6~-[(1Z)-ethanimidoyl]-4-fluoro-L-lysine; (2S,4R)-2-amino-6-ethanimidamido-4-fluorohexanoic acid; (2S,4R)-2-amino-6-(1-aminoethylideneamino)-4-fluorohexanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 448269
TTD Drug ID: DMUGFS3

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Nitric-oxide synthase inducible (NOS2)	TTF10I9	NOS2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Nitric-oxide synthase inducible (NOS2)	DTT	NOS2	4.95	5.198	4.573	5.121

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Nitric-oxide synthase inducible (NOS2)	DTT	NOS2	4.24E-02	-0.27	-0.88

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.