Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMUJ18P)

Drug Name

N-methyl-1-(2-thiophen-2-ylphenyl)methanamine Drug Info

Synonyms

N-Methyl-N-(2-thien-2-ylbenzyl)amine; 852180-66-6; N-methyl-1-(2-thiophen-2-ylphenyl)methanamine; CHEMBL549343; N-Methyl-2-thien-2-ylbenzylamine; N-methyl-1-(2-(thiophen-2-yl)phenyl)methanamine; AC1OEOYY; CTK5F4550; DTXSID00427632; MolPort-000-143-044; HMS3604E04; ZINC3880928; SBB093177; BDBM50294171; AKOS010337666; RP04434; DB07196; n-methyl-n-(2-thiophen-2-ylbenzyl)amine; methyl[(2-(2-thienyl)phenyl)methyl]amine; KB-204244; KB-302285; RT-014485; Benzenemethanamine,N-methyl-2-(2-thienyl)-; Y4269; Benzenemethanamine, N-methyl-2-(2

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 7060565
CAS Number: CAS 852180-66-6
TTD Drug ID: DMUJ18P

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukotriene A-4 hydrolase (LTA4H)	TTXZEAJ	LKHA4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	7.338	7.827	8.134	8.612

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	1.31E-48	-1.22	-2.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.