Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMV2CKN)

Drug Name

(4-(thiophen-2-yl)phenyl)methanamine Drug Info

Synonyms

4-(2-Thienyl)benzylamine; 4-(2-THIENYL)BENZYLAMINE; 203436-48-0; 1-(4-thiophen-2-ylphenyl)methanamine; [4-(Thiophen-2-Yl)Phenyl]Methanamine; CHEMBL539640; Benzenemethanamine,4-(2-thienyl)-; Benzenemethanamine, 4-(2-thienyl)-; SDCCGMLS-0065961P001; AC1MCQW2; AC1Q53XJ; 4-(2-thienyl) benzylamine; 4-(Thien-2-yl)benzylamine; SCHEMBL112455; CTK4E3973; DTXSID90379994; YKNLMMDEWQZCLJ-UHFFFAOYSA-N; MolPort-000-142-431; HMS3604G04; ZINC158702; (4-(2-thienyl)phenyl)methylamine; (4-thiophen-2-ylphenyl)methanamine; SBB091000

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 2776332
CAS Number: CAS 203436-48-0
TTD Drug ID: DMV2CKN

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Leukotriene A-4 hydrolase (LTA4H)	TTXZEAJ	LKHA4_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	7.338	7.827	8.134	8.612

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Leukotriene A-4 hydrolase (LTA4H)	DTT	LTA4H	1.31E-48	-1.22	-2.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.