Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMV8ZFA)

Drug Name

PMID20080612C1 Drug Info

Synonyms

BAS 00486818; tg3-95-1; 301322-12-3; AC1LDROW; Oprea1_785181; Oprea1_405733; MLS000107338; GTPL5819; ZINC35938; MolPort-000-222-632; CHEBI:112974; HMS2485P23; CCG-17500; BDBM50016951; STK386484; AKOS000513935; MCULE-3137850852; SMR000111709; ST005800; KB-275480; SR-01000448413; SR-01000448413-1; F0817-0357; ethyl 2-(furan

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 673766
ChEBI ID: CHEBI:112974
TTD Drug ID: DMV8ZFA

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin E2 receptor EP2 (PTGER2)	TT1ZAVI	PE2R2_HUMAN	Modulator (allosteric modulator)	[1]

------------------------------------------------------------------------------------

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin E2 receptor EP2 (PTGER2)	DTT	PTGER2	4.75	5.888	5.066	4.466

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin E2 receptor EP2 (PTGER2)	DTT	PTGER2	2.77E-06	1.15	1.37

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2307-12.