Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMVJDCM)

Drug Name
PSX-4206 Drug Info
Synonyms PSX-4159; VAP1 inhibitor (lung disease), Pharmaxis; Vascular adhesion protein-1 inhibitor (lung disease), Pharmaxis
Indication
Disease Entry ICD 11 Status REF
Pulmonary disease 1B10-1F85 Investigative [1]
Cross-matching ID
TTD Drug ID
DMVJDCM

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Membrane copper amine oxidase (AOC3) TT7HC21 AOC3_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Membrane copper amine oxidase (AOC3) DTT AOC3 7.055 8.263 6.709 7.374
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Pulmonary disease
ICD Disease Classification 1B10-1F85
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Membrane copper amine oxidase (AOC3) DTT AOC3 8.36E-22 -1.03 -1.54
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).