Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMWD42N)

Drug Name

4-fluorobenzoyl-Phe-Gly-Leu-Arg-Trp-NH2 Drug Info

Synonyms

CHEMBL388586; Peptide analogue, 1; SCHEMBL4132720; BDBM26338; FTM-080; N-[(4-fluorophenyl)carbonyl]-L-phenylalanylglycyl-L-leucyl-L-arginyl-L-tryptophanamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 16735569
TTD Drug ID: DMWD42N

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
G-protein coupled receptor 54 (KISS1R)	TT3KBZY	KISSR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
G-protein coupled receptor 54 (KISS1R)	DTT	KISS1R	2.51E-03	0.74	0.91

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase. J Med Chem. 2008 Dec 11;51(23):7645-9.