General Information of Drug (ID: DMWF8U5)

Drug Name
EX-1314 Drug Info
Synonyms BMS-317180; BMS-604992; BMS-606056; Ghrelin agonists, BMS; Ghrelin agonists, Elixir; Growth hormone secretagogues, BMS; Growthhormone secretagogues, Elixir
Indication
Disease Entry ICD 11 Status REF
Cachexia MG20 Investigative [1]
Cross-matching ID
PubChem CID
72941845
CAS Number
CAS 674343-47-6
TTD Drug ID
DMWF8U5

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Growth hormone secretagogue receptor 1 (GHSR) TTWDC17 GHSR_HUMAN Agonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 2.609 4.104 4.797 1.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Cachexia
ICD Disease Classification MG20
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 4.56E-01 -0.14 -0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).