General Information of Drug (ID: DMX6V1L)

Drug Name
ST-1141 Drug Info
Synonyms Ghrelin agonist (oral, opioid-induced bowel dysfunction), Helsinn
Indication
Disease Entry ICD 11 Status REF
Functional bowel disorder DD91 Phase 1 [1]
Cross-matching ID
PubChem CID
11061233
TTD Drug ID
DMX6V1L

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Growth hormone secretagogue receptor 1 (GHSR) TTWDC17 GHSR_HUMAN Agonist [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 2.609 4.104 4.797 1.485
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Functional bowel disorder
ICD Disease Classification DD91
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Growth hormone secretagogue receptor 1 (GHSR) DTT GHSR 4.56E-01 -0.14 -0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025998)
2 The Prokinetic Face of Ghrelin. International Journal of Peptides Volume 2010 (2010), Article ID 493614, Page(11).