Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXA4HY)

Drug Name
Poly IC-poly arginine Drug Info
Synonyms Poly-ICR vaccine adjuvant, Akela; Poly-ICR vaccine adjuvant, Nventa; Poly(inosinic-cytidylic) acid-poly arginine
Indication
Disease Entry ICD 11 Status REF
Keratosis ED56 Investigative [1]
Cross-matching ID
TTD Drug ID
DMXA4HY

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Toll-like receptor 3 (TLR3) TTD24Y0 TLR3_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Toll-like receptor 3 (TLR3) DTT TLR3 4.256 5.833 5.916 6.583
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Keratosis
ICD Disease Classification ED56
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Toll-like receptor 3 (TLR3) DTT TLR3 4.85E-01 0.63 0.83
Toll-like receptor 3 (TLR3) DTT TLR3 8.00E-01 0.11 0.1
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1753).