Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXBQRJ)

Drug Name
Glu-Leu-Asp-Leu-(CHOH-CH2)-Ala-Ala-Glu-Phe Drug Info
Synonyms CHEMBL363255; Glu-Leu-Asp-Leu-(CHOH-CH2)-Ala-Ala-Glu-Phe
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
44397266
TTD Drug ID
DMXBQRJ

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Beta-secretase (BACE) TT8JRS7 NOUNIPROTAC Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Beta-secretase (BACE) DTT BACE 5.928 4.638 6.443 5.3
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Beta-secretase (BACE) DTT NO-GeName 6.98E-04 1.03 2.84
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Efficient evaluation of binding free energy using continuum electrostatics solvation. J Med Chem. 2004 Nov 4;47(23):5791-7.