Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXCJ7O)

Drug Name
Prostacyclin analog Drug Info
Synonyms Prostacyclin analog (deuterated, pulmonary hypertension)
Indication
Disease Entry ICD 11 Status REF
Pulmonary hypertension BB01 Investigative [1]
Cross-matching ID
TTD Drug ID
DMXCJ7O

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostacyclin receptor (PTGIR) TTOFYT1 PI2R_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Prostacyclin receptor (PTGIR) DTT PTGIR 6.384 3.7 4.684 4.603
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Pulmonary hypertension
ICD Disease Classification BB01
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Prostacyclin receptor (PTGIR) DTT PTGIR 7.12E-02 -0.13 -0.33
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 345).