Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXD8H1)

Drug Name

(1-Amino-2-phenyl-ethyl)-phosphinic acid Drug Info

Synonyms

CHEMBL37846; 80744-66-7; (1-AMINO-2-PHENYLETHYL)PHOSPHINIC ACID; Phosphinic acid, (1-amino-2-phenylethyl)-; AC1O49RT; MLS004256549; SCHEMBL3862224; CTK5E8078; DTXSID90422994; APQRSTHZZSRXIS-UHFFFAOYSA-N; AKOS006273173; SMR003081569; (1-amino-2-phenylethyl)-hydroxy-oxophosphanium; Phosphinic acid,(1-amino-2-phenylethyl)- (9CI)

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 54297424
TTD Drug ID: DMXD8H1

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aminopeptidase N (ANPEP)	TTPHMWB	AMPN_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.744	7.809	8.914	11.49

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aminopeptidase N (ANPEP)	DTT	ANPEP	8.84E-07	-0.3	-0.71

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6.