Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXDGEF)

Drug Name

2-(2-allyl-4-chlorophenoxy)acetic acid Drug Info

Synonyms

CHEMBL245707; 6964-26-7; (2-allyl-4-chloro-phenoxy)-acetic acid; NSC66309; [4-chloro-2-(prop-2-en-1-yl)phenoxy]acetic acid; 2-(2-allyl-4-chlorophenoxy)acetic acid; AC1Q3LUZ; 2-(4-chloro-2-prop-2-enylphenoxy)acetic acid; AC1L6N6K; SCHEMBL4879038; CTK5D0709; DTXSID60290061; NSC-66309; BDBM50213925; AKOS005352797; Acetic acid,2-[4-chloro-2-(2-propen-1-yl)phenoxy]-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 248828
CAS Number: CAS 6964-26-7
TTD Drug ID: DMXDGEF

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Prostaglandin D2 receptor 2 (PTGDR2)	TTQDMX5	PD2R2_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Prostaglandin D2 receptor 2 (PTGDR2)	DTT	PTGDR2	4.436	5.954	4.217	4.641

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Prostaglandin D2 receptor 2 (PTGDR2)	DTT	PTGDR2	6.11E-02	-0.15	-0.25

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4347-50.