Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXIU6W)

Drug Name

Quercetin 3-O-neohesperidoside Drug Info

Synonyms

quercetin 3-O-neohesperidoside; q-Rha-gal; CHEMBL499824; 117611-67-3; Quercetin 3-O-alpha-rhamnopyranosyl-(1-2)-beta-galactopyranoside; AC1NX8PX; DTXSID60151840; BDBM50260169; 3',4',5,7-Tetrahydroxy-3-(2-O-alpha-L-rhamnopyranosyl-beta-D-galactopyranosyloxy)flavone; 4H-1-Benzopyran-4-one, 3-((2-O-(6-deoxy-alphal-L-manopyranosyl)-beta-D-galactopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5748416
CAS Number: CAS 117611-67-3
TTD Drug ID: DMXIU6W

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Aldose reductase (AKR1B1)	TTFBNVI	ALDR_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Aldose reductase (AKR1B1)	DTT	AKR1B1	7.436	8.652	9.874	8.066

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Aldose reductase (AKR1B1)	DTT	AKR1B1	1.08E-20	0.94	1.58

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Pru... J Nat Prod. 2002 Aug;65(8):1151-5.