Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMXQGKL)

Drug Name

CB-813 Drug Info

Synonyms

CB-813d; Recombinant human factor VIIa (Alterase, hemophilia), Catalyst Biosciences; RhFVIIa (Alterase, hemophilia), Catalyst Biosciences; Recombinant human factor VIIa (Alterase, hemophilia), Catalyst Biosciences/Wyeth Pharmaceuticals

Indication

Disease Entry	ICD 11	Status	REF
Hemophilia	3B10.0	Phase 1	[1]

Cross-matching ID

PubChem CID: 208688
CAS Number: CAS 32808-74-5
TTD Drug ID: DMXQGKL

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor VII (F7)	TTF0EGX	FA7_HUMAN	Modulator	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Coagulation factor VII (F7)	DTT	F7	9.218	4.853	5.6	5.747

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Hemophilia

ICD Disease Classification

3B10.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor VII (F7)	DTT	F7	2.52E-01	-0.03	-0.19

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027663)
2	Clinical pipeline report, company report or official report of Catalyst Biosciences.