Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY0DPM)

Drug Name
ARC-1905 Drug Info
Synonyms Aptamer C5 inhibitors (age-related macular degeneration), Archemix/Ophthotech
Indication
Disease Entry ICD 11 Status REF
Macular degeneration 9B78.3 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMY0DPM

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement C5 (CO5) TTKANGO CO5_HUMAN Not Available [1]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Macular degeneration
ICD Disease Classification 9B78.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement C5 (CO5) DTT C5 7.69E-01 -0.12 -0.23
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT00950638) A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration. U.S. National Institutes of Health.