Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY6NID)

Drug Name

Des-AA1,2,5-[(NalphaMe)Cys3,D-Trp8,IAmp9]SRIF Drug Info

Synonyms

CHEMBL265120; Des-AA1,2,5-[(NalphaMe)Cys3,D-Trp8,IAmp9]SRIF

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Somatostatin receptor type 1 (SSTR1)	TTIND6G	SSR1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Somatostatin receptor type 1 (SSTR1)	DTT	SSTR1	5.588	3.392	4.087	4.009

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Somatostatin receptor type 1 (SSTR1)	DTT	SSTR1	2.39E-14	-0.6	-0.83

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan. J Med Chem. 2005 Jan 27;48(2):507-14.