Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY7WH1)

Drug Name
Sutimlimab Drug Info
Indication
Disease Entry ICD 11 Status REF
Cold type autoimmune haemolytic anemia 3A20.1 Approved [1]
Cross-matching ID
TTD Drug ID
DMY7WH1

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement C1s component (C1S) TT7LRQH C1S_HUMAN Inhibitor [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Complement C1s component (C1S) DTT C1S 12.194 10.051 9.335 8.798
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Cold type autoimmune haemolytic anemia
ICD Disease Classification 3A20.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Complement C1s component (C1S) DTT C1S 5.50E-01 1.09 0.91
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 761164.
2 Antibodies to watch in 2020. MAbs. Jan-Dec 2020;12(1):1703531.