Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMY9DA3)

Drug Name
SLV-332 Drug Info
Synonyms AC1MHEA6; Isoxyl &amp
Indication
Disease Entry ICD 11 Status REF
Irritable bowel syndrome DD91.0 Preclinical [1]
Cross-matching ID
PubChem CID
3002337
TTD Drug ID
DMY9DA3

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Substance-K receptor (TACR2) TTYO0A3 NK2R_HUMAN Antagonist [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Substance-K receptor (TACR2) DTT TACR2 2.807 7.373 5.433 6.018
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Irritable bowel syndrome
ICD Disease Classification DD91.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Substance-K receptor (TACR2) DTT TACR2 6.83E-01 -2.22E-03 -0.01
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.