General Information of Drug (ID: DMYBNCO)

Drug Name
7-bromo-1H-indazole Drug Info
Synonyms
7-bromo-1H-indazole; 53857-58-2; 7-Bromoindazole; 7-Bromo-2H-indazole; 845751-59-9; 1H-Indazole, 7-bromo-; 1H-INDAZOLE,7-BROMO-; CHEMBL439566; AK-26850; PubChem14406; 2H-Indazole, 7-bromo-; ACMC-1B1ZL; BROMOINDAZOLE(7-); T56 BMNJ IE; KSC268A6L; 7-Bromo-1H-indazole, 97%; SCHEMBL1855857; CTK1G8065; MolPort-027-946-828; MolPort-006-717-407; KMHHWCPTROQUFM-UHFFFAOYSA-N; ZX-AT005164; BCP00108; STL555654; 2999AC; FCH835100; ANW-31868; ZINC14007945; MFCD07371564; BBL101857; SBB092096; BDBM50209239; AKOS016013628; AKOS005072291; RTC-062730; RP04094
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
20323899
CAS Number
CAS 53857-58-2
TTD Drug ID
DMYBNCO

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nitric-oxide synthase brain (NOS1) TTZUFI5 NOS1_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Nitric-oxide synthase brain (NOS1) DTT NOS1 6.085 5.844 5.849 5.806
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nitric-oxide synthase brain (NOS1) DTT NOS1 5.20E-01 0.02 0.07
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80.