Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYDGH4)

Drug Name

4-((1H-imidazol-1-yl)methyl)phenol Drug Info

Synonyms

4-(1h-imidazol-1-ylmethyl)phenol; 1-(4-Hydroxybenzyl)imidazole; 41833-17-4; 4-((1H-imidazol-1-yl)methyl)phenol; Phenol, 4-(1H-imidazol-1-ylmethyl)-; CHEMBL166845; ZEFROCQEWXHIEP-UHFFFAOYSA-N; 4-(imidazolylmethyl)phenol; 4-Hobi; n-p-hydroxybenzylimidazole; AC1L4X2E; AC1Q7A8C; 4-Imidazol-1-ylmethyl-phenol; 4-(1h-imidazolylmethyl)phenol; 4-(imidazol-1-ylmethyl)phenol; SCHEMBL6323414; 4-[(1-imidazolyl)methyl]phenol; CTK4I5281; DTXSID30194643; MolPort-006-827-429; 1-(4-Hydroxybenzyl)-1H-imidazole; ZINC13549136; SBB051635

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 193822
CAS Number: CAS 41833-17-4
TTD Drug ID: DMYDGH4

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Steroid 17-alpha-monooxygenase (S17AH)	TTRA5BZ	CP17A_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Steroid 17-alpha-monooxygenase (S17AH)	DTT	CYP17A1	6.213	5.615	6.895	6.025

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Steroid 17-alpha-monooxygenase (S17AH)	DTT	CYP17A1	6.87E-01	0.07	0.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as pote... Bioorg Med Chem Lett. 2010 Sep 1;20(17):5345-8.