Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYHIAR)

Drug Name

AdRTVP-1 Drug Info

Synonyms

AdRTVP-1, Baylor College of Medicine; Gene therapy (RTVP-1); Gene therapy (RTVP-1), Baylor College of Medicine; Related to Testes-Specific Vespid and Pathogenesis Protein-1 adenoviral gene therapy, BCM

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1	[1]

Cross-matching ID

TTD Drug ID: DMYHIAR

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glioma pathogenesis-related protein 1 (GLIPR1)	TTEQF1O	GLIP1_HUMAN	Modulator	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Glioma pathogenesis-related protein 1 (GLIPR1)	DTT	GLIPR1	5.3	5.492	5.399	5.564

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification

02 Neoplasm

Disease Class

ICD-11: 2C82 Prostate cancer

The Studied Tissue

Prostate

The Studied Disease

Prostate cancer [ICD-11:2C82]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glioma pathogenesis-related protein 1 (GLIPR1)	DTT	GLIPR1	8.91E-01	0.43	0.45

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Adenoviral vector-mediated RTVP-1 gene-modified tumor cell-based vaccine suppresses the development of experimental prostate cancer. Cancer Gene Ther. 2006 Jul;13(7):658-63.