Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYOAKS)

Drug Name

Teduglutide Drug Info

Synonyms

Gattex (TN)

Indication

Disease Entry	ICD 11	Status	REF
Short bowel syndrome	KB89.1	Approved	[1]

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Glucagon-like peptide 2 receptor (GLP2R)	TT1YWO5	GLP2R_HUMAN	Modulator	[2]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Glucagon-like peptide 2 receptor (GLP2R)	DTT	GLP2R	1.807	2.138	2.202	2.632

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Short bowel syndrome

ICD Disease Classification

KB89.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Glucagon-like peptide 2 receptor (GLP2R)	DTT	GLP2R	6.12E-01	0.06	0.3

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7049).
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015