Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMYPXQ2)

Drug Name
CVBT-141H Drug Info
Synonyms
CVBT-141A; CVBT-141C; CVBT-141C); Cardio Vascu-Grow; FGF-1-141; Recombinant FGF-1 (coronary heart disease), CardioVascular Therapeutics; Recombinant FGF-1 (peripheral vascular disease), CardioVascular biotherapeutics
Indication
Disease Entry ICD 11 Status REF
Coronary artery disease BA80 Phase 2 [1]
Coronary heart disease BA80.Z Phase 2 [2]
Peripheral arterial disease BD4Z Phase 2 [2]
Cross-matching ID
TTD Drug ID
DMYPXQ2

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heparin-binding growth factor 1 (FGF1) TTMY81X FGF1_HUMAN Modulator [3]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Heparin-binding growth factor 1 (FGF1) DTT FGF1 5.35 4.717 6.95 4.966
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 11 Disease of the circulatory system
Disease Class ICD-11: BA80 Coronary artery disease
The Studied Tissue Peripheral blood
The Studied Disease Coronary artery disease [ICD-11:BA80-BA8Z]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heparin-binding growth factor 1 (FGF1) DTT FGF1 9.56E-01 -0.02 -0.11
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020529)
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of CVBT.