Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZ3X7F)

Drug Name
Fordadistrogene movaparvovec Drug Info
Synonyms PF-06939927
Indication
Disease Entry ICD 11 Status REF
Duchenne muscular dystrophy 8C70.1 Phase 3 [1]
Cross-matching ID
TTD Drug ID
DMZ3X7F

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dystrophin (DMD) TT48MP6 DMD_HUMAN Not Available [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Dystrophin (DMD) DTT DMD 6.356 5.446 5.459 5.326
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Duchenne muscular dystrophy
ICD Disease Classification 8C70.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dystrophin (DMD) DTT DMD 1.15E-07 -1.07 -2.94
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 ClinicalTrials.gov (NCT05689164) Long-term Follow-up Safety and Efficacy Study in Participants With Duchenne Muscular Dystrophy Who Have Received Fordadistrogene Movaparvovec in a Preceding Clinical Study. U.S.National Institutes of Health.