Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZNFT2)

Drug Name

Phenylalanylmethane Drug Info

Synonyms

PHENYLALANYLMETHANE; 2-Butanone, 3-amino-4-phenyl-, (S)-; 52735-74-7; AC1NRCRL; SCHEMBL4379939; SCHEMBL1436467; CTK1G2192; DTXSID60415353; ZINC5883734; (3S)-3-amino-4-phenylbutan-2-one; AKOS006340967

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 5289150
CAS Number: CAS 52735-74-7
TTD Drug ID: DMZNFT2

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Chymase (CYM)	TT8VUE0	CMA1_HUMAN	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Chymase (CYM)	DTT	CMA1	2.848	4.517	4.615	3.406

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Chymase (CYM)	DTT	CMA1	3.36E-05	-0.62	-3.21

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.