Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZOX43)

Drug Name

(2S)-2'-methoxy kurarinone Drug Info

Synonyms

2'-Methoxykurarinone; (2S)-2'-methoxykurarinone; 270249-38-2; CHEMBL496451; CHEBI:66151; (2S)-2'-methoxy kurarinone; (2S)-7,4'-Dihydroxy-8-lavandulyl-5,2'-dimethoxyflavanone; MolPort-039-337-150; ZINC14711635; LMPK12140500; BDBM50377944; AKOS032962578; 7,4'-dihydroxy-5,2'-dimethoxy-8-lavandulylflavanone; 4H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-2-(4-hydroxy-2-methoxyphenyl)-5-methoxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexenyl]-, (2S)-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 11982641
ChEBI ID: CHEBI:66151
TTD Drug ID: DMZOX43

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Beta-secretase (BACE)	TT8JRS7	NOUNIPROTAC	Inhibitor	[1]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Beta-secretase (BACE)	DTT	BACE	5.928	4.638	6.443	5.3

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Discovery agent

ICD Disease Classification

N.A.

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Beta-secretase (BACE)	DTT	NO-GeName	6.98E-04	1.03	2.84

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	BACE1 inhibitory effects of lavandulyl flavanones from Sophora flavescens. Bioorg Med Chem. 2008 Jul 15;16(14):6669-74.