Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZQBCL)

Drug Name
LR3001 Drug Info
Indication
Disease Entry ICD 11 Status REF
Myeloid leukaemia 2B33.1 Phase 2 [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
TTD Drug ID
DMZQBCL

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myb messenger RNA (MYB mRNA) TT8V13P MYB_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Myb messenger RNA (MYB mRNA) DTT MYB 3.695 7.071 4.178 5.884
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Myeloid leukaemia
ICD Disease Classification 2B33.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Myb messenger RNA (MYB mRNA) DTT MYB 1.07E-11 0.34 0.74
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Pipeline report of Genta.
2 Genta obtains orphan drug designation for C-Myb Antisense (LR3001) in chronic myelocytic leukemia. Genta. 2005.