Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZU4O8)

Drug Name
TKP-1002 Drug Info
Synonyms Antipsychotics (schizophrenia), EUSA Pharma; Antipsychotics (schizophrenia), Talisker Pharma; Antipsychotics (schizophrenia), University of Liege
Indication
Disease Entry ICD 11 Status REF
Schizophrenia 6A20 Investigative [1]
Cross-matching ID
TTD Drug ID
DMZU4O8

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D4 receptor (D4R) TTE0A2F DRD4_HUMAN Modulator [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Dopamine D4 receptor (D4R) DTT DRD4 2.138 1.766 1.322 1
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Schizophrenia
ICD Disease Classification 6A20
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine D4 receptor (D4R) DTT DRD4 1.90E-01 0.19 0.76
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 217).